PGT is a way to learn more about the health of an embryo before it’s transferred. It is used to help the physicians and embryologists understand aspects of the embryo’s makeup that could influence the chance of a successful pregnancy. While it doesn’t promise outcomes, it can help reduce uncertainty and guide families in selecting the embryo most likely to thrive.
While PGT-A looks for missing or extra chromosomes, there are additional PGT tests that look for specific inherited abnormalities and can be performed either for inherited genetic diseases or for inherited chromosome rearrangements.
Preimplantation Genetic Testing for Monogenic/Single-Gene Disorders (PGT-M) is performed when a patient has an increased risk for a specific genetic condition that can be passed onto his or her children, or for women who are carriers for an X-linked condition, or when an individual and their partner are both carriers for the same autosomal recessive condition. These include specific inherited conditions controlled by a single gene such as Huntington’s disease, sickle-cell disease, or Fragile X syndrome.
Preimplantation Genetic Testing for Chromosomal Structural Rearrangements (PGT-SR) is performed when a patient or their partner has a rearrangement of their own chromosomes. It looks for specific inherited chromosome abnormalities, like reciprocal translocations, Robertsonian translocations, or inversions. Embryos with missing or extra pieces of chromosomes are more likely to result in a miscarriage or a child with serious health issues.
PatientFi has teamed up with The Center for Advanced Reproductive Services to make fertility care more accessible and affordable—so nothing stands in your way. When you’re ready to start your fertility journey, cost shouldn’t hold you back.
